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LITHOCHOLIC ACID |
| Synonyms. Lithocholic acid; (3-alpha,5-beta)-3-Hydroxycholan-24-oic acid; 17-beta-(1-Methyl-3-carboxypropyl)ethiocholan-3-alpha-ol; 17beta-(1-Methyl-3-carboxypropyl)etiocholan-3alpha-ol; 3-alpha-Hydroxy-5-beta-cholanic acid; 3-alpha-Hydroxycholanic acid; 3-Hydroxycholan-24-oic acid; 3alpha-Hydroxy-5beta-cholan-24-oic acid; 3alpha-Hydroxy-5beta-cholanic acid; 3alpha-Hydroxycholanic acid; |
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| PRODUCT IDENTIFICATION | |
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CAS RN |
434-13-9 |
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EINECS RN |
207-099-1 |
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FORMULA |
C24H40O3 |
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MOLE WEIGHT |
376.57 |
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H.S CODE |
2918.19.9000 |
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SMILES |
C1[C@@]2([C@H](CC[C@H]2[C@@H]2CC[C@H]3[C@@](CC[C@H](O)C3) (C) [C@@H]2C1) [C@@H](CCC(=O)O)C)C |
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CLASSIFICATION |
Bile acid |
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EXTRA NOTES |
A bile acid formed from chenodeoxycholate by bacterial action, usually conjugated with glycine or taurine. It acts as a detergent to solubilize fats for absorption and is itself absorbed. It is used as cholagogue and choleretic. |
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| PHYSICAL AND CHEMICAL PROPERTIES | |
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PHYSICAL STATE |
white to off-white crystalline powder |
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MELTING POINT |
180 ~ 188 C |
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BOILING POINT |
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DENSITY |
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SOLUBILITY IN WATER |
Insoluble |
| SOLVENT SOLUBILITY |
Slightly soluble in glacial acetic acid. Soluble in ethyl acetate, alcohol |
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VAPOR DENSITY |
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log P(octanol-water) |
6.19 |
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VAPOR PRESSURE |
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AUTOIGNITION TEMP |
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REFRACTIVE INDEX |
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FLASH POINT |
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| STABILITY AND REACTIVITY | |
| STABILITY | Stable under normal conditions. |
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INCOMPATIBLE MATERIALS |
Strong oxidizing agents. |
| POLYMERIZATION |
Has not been reported |
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NFPA RATINGS |
Health: 1, Flammability: 0, Reactivity: 0 |
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| EXTERNAL LINKS & GENERAL DESCRIPTION |
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USA.gov - Lithocholic acid Wikipedia Linking - Lithocholic acid Google Scholar Search - Lithocholic acid U.S. National Library of Medicine - Lithocholic acid PubChem Compound Summary - Lithocholic acid KEGG (Kyoto Encyclopedia of Genes and Genomes) - Lithocholic acid ChEBI (http://www.ebi.ac.uk/chebi/) - Lithocholic acid NCBI (http://www.ncbi.nlm.nih.gov/) - Lithocholic acid Material Safety Data Sheet - Lithocholic acid Hazardous Substances Data Bank - Lithocholic acid EPA - Substance Registry Services - Lithocholic acid |
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| SALES SPECIFICATION | |
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APPEARANCE |
white to off-white crystalline powder |
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ASSAY |
98% min |
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MELTING POINT |
183 ~ 188 C |
| OPTICAL ROTATION |
+32° ~ +36° (c=1.5, EtOH) |
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LOSS ON DRYING |
1% max |
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HEAVY METALS |
10ppm max |
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| TRANSPORT & REGULATORY INFORMATION | |
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| SAFETY INFORMATION | |
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HAZARD OVERVIEW |
GHS (Globally Harmonised System) Classification: Acute toxicity (Oral). Hazard statements: Harmful if swallowed. |
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| PACKING |
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Preserved in light-resistant and well-closed bottles |
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